Black cumin (Nigella sativa) is an annual flowering plant in the family Ranunculaceae that beside medicinal value was used as food and cosmetics products. Salicylic acid is a growth regulator with phenolic nature has main role in regulation of many physiological processes and resistance to environmental stress. In order to study effect of salt stress and salicylic acid on some growth parameters including chlorophyll a, chlorophyll b, total chlorophyll, carotenoid, proline, malondialdehyde (MDA),  other aldehydes, gayvkl peroxidase and lipoxygenase in medicinal plant Nigella (Nigella sativa L.), an experiment was conducted in factorial design based on complementary randomized design in 2016 at greenhouse of Ilam university. Treatments were include salinity at three level (Zero, 25 and 75 mM) and salicylic acid at three level (Zero, 0.75 and 1.5 mM) respectively. The results showed that salt stress decreased chlorophyll a, chlorophyll b, total chlorophyll, carotenoids and a significant increase in proline, malondialdehyde (MDA) and other aldehydes. Black cumin is sensitive to salinity stress, so by applying salicylic acid antioxidant capacity of the plants were increased against stress conditions.